兔抗PPP1R8多克隆抗体

Background:

This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.

Applications:

WB

Name of antibody:

PPP1R8

Immunogen:

Synthesized peptide derived from internal of human PPP1R8.

Full name:

protein phosphatase 1, regulatory subunit 8

Synonyms：

ARD1; ARD-1; NIPP1; NIPP-1; PRO2047

SwissProt:

Q12972

WB Predicted band size:

38 kDa

WB Positive control:

Jurkat cells lysate

WB Recommended dilution:

500-3000