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技术规格
Background:
This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect.
Applications:
ELISA, WB, IHC
Name of antibody:
SLC1A1
Immunogen:
Synthetic peptide of human SLC1A1
Full name:
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
Synonyms:
DCBXA; EAAC1; EAAT3; SCZD18
SwissProt:
P43005
ELISA Recommended dilution:
2000-5000
IHC positive control:
Human liver cancer and Human breast cancer
IHC Recommend dilution:
25-100
WB Predicted band size:
57 kDa
WB Positive control:
Human placenta tissue and normal liver tissue
WB Recommended dilution:
500-2000