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中文名称: 兔抗Synpr多克隆抗体
英文名称: Anti-Synpr rabbit polyclonal antibody
别 名: synaptoporin
相关类别: 一抗
储 存: 冷冻(-20℃) 避光
宿 主: Rabbit
抗 原: Synpr
反应种属: Human, Mouse, Rat
标 记 物 : Unconjugate
克隆类型: rabbit polyclonal
技术规格
Background:
Synaptophysin (SYP) is a neuronal synaptic vesicle glycoprotein that is expressed in neuroendocrine cells and neoplasms, and thus can be used as a marker in tumor diagnosis (1). Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore (2). Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases (3). Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex (4).
Applications:
WB
Name of antibody:
Synpr
Immunogen:
Synthetic peptide of Rat Synpr
Full name:
Synpr
Synonyms:
synaptoporin
SwissProt:
P22831
WB Predicted band size:
29 kDa
WB Positive control:
Rat brain and mouse brain
WB Recommended dilution:
500-1000