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Background:
The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.
Applications:
ELISA, IHC
Name of antibody:
GSN
Immunogen:
Synthetic peptide of human GSN
Full name:
gelsolin
Synonyms:
ADF, AGEL
SwissProt:
P06396
ELISA Recommended dilution:
1000-2000
IHC positive control:
Human brain and Human thyroid cancer
IHC Recommend dilution:
25-100