兔抗PTK2 (phospho-Tyr576 Tyr577)多克隆抗体

Background:

Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity.

Applications:

WB, IF

Name of antibody:

PTK2 (phospho-Tyr576/Tyr577)

Immunogen:

Synthetic peptide of human PTK2 (phospho-Tyr576/Tyr577)

Full name:

protein tyrosine kinase 2 (phospho-Tyr576/Tyr577)

Synonyms：

FAK; FADK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK

SwissProt:

Q05397

WB Predicted band size:

125 kDa

WB Positive control:

HT29 cells treated with PMA

WB Recommended dilution:

500-1000

IF Positive control:

Hela cells

IF Recommended dilution

100-200