兔抗NR3C1(Ab-226)多克隆抗体

Background:

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus.

Applications:

WB, IHC

Name of antibody:

NR3C1(Ab-226)

Immunogen:

Synthesized non-phosphopeptide derived from human GR around the phosphorylation site of serine 226/234/246 (L-L-S-P-L).

Full name:

nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

Synonyms：

GR; GCR; GRL; GCCR; GCRST

SwissProt:

P04150

IHC positive control:

Human brain tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

86 kDa

WB Positive control:

Jurkat cells treated with EGF (200ng/ml, 15mins) lysate

WB Recommended dilution:

500-3000