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Background: |
The protein encoded by this gene is a component of the RNA polymerase I and RNA polymerase III complexes, which function in the synthesis of ribosomal RNA precursors and small RNAs, respectively. Mutations in this gene are a cause of Treacher Collins syndrome (TCS), a craniofacial development disorder. Alternative splicing results in multiple transcript variants. |
Applications: |
ELISA, IHC |
Name of antibody: |
POLR1D |
Immunogen: |
Fusion protein of human POLR1D |
Full name: |
RNA polymerase I subunit D |
Synonyms: |
AC19; RPA9; TCS2; RPA16; RPAC2; RPC16; POLR1C; RPO1-3 |
SwissProt: |
P0DPB5 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human esophagus cancer and Human liver cancer |
IHC Recommend dilution: |
25-100 |