兔抗PCBP4多克隆抗体

WB Recommended dilution:

200-1000

WB Positive control:

Mouse kidney tissue

WB Predicted band size:

41 kDa

SwissProt:

P57723

Synonyms:

CBP; LIP4; MCG10

Full name:

poly(rC) binding protein 4

Immunogen:

Synthetic peptide of human PCBP4

Name of antibody:

PCBP4

Applications:

ELISA, WB

Background:

This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the encoded protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G(2)-M. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Multiple alternatively spliced transcript variants have been described, but the full-length nature for only some has been determined. [provided by RefSeq, Jul 2008]