兔抗STX1A多克隆抗体

Background:

This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

STX1A

Immunogen:

Synthetic peptide of human STX1A

Full name:

Syntaxin 1A (brain)

Synonyms：

STX1; HPC-1; P35-1; SYN1A

SwissProt:

Q16623

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human ovarian cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

33 kDa

WB Positive control:

Mouse brain tissue

WB Recommended dilution:

1000-5000