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英文名称: Anti-STAT6 rabbit polyclonal antibody
别 名: STAT6B; STAT6C; D12S1644; IL-4-STAT
相关类别: 一抗
抗 原: STAT6
储 存: 冷冻(-20℃)
宿 主: Rabbit
反应种属: Human, Mouse
标 记 物 : Unconjugate
克隆类型: rabbit polyclonal
技术规格
Background:
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.
Applications:
ELISA, WB
Name of antibody:
STAT6
Immunogen:
Fusion protein of human STAT6
Full name:
signal transducer and activator of transcription 6, interleukin-4 induced
Synonyms:
STAT6B; STAT6C; D12S1644; IL-4-STAT
SwissProt:
P42226
ELISA Recommended dilution:
2000-5000
WB Predicted band size:
94 kDa
WB Positive control:
Raji cells
WB Recommended dilution:
500-2000