兔抗PRKCD (Phospho-Ser645)多克隆抗体

Background:

This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. May play a role in antigen-dependent control of B-cell function. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin.

Applications:

WB, IHC

Name of antibody:

PRKCD (Phospho-Ser645)

Immunogen:

Synthetic peptide of human PRKCD (Phospho-Ser645)

Full name:

protein kinase C, delta (Phospho-Ser645)

Synonyms：

MAY1; PKCD; nPKC-delta

SwissProt:

Q05655

IHC positive control:

Human breast carcinoma

IHC Recommend dilution:

50-100

WB Predicted band size:

78 kDa

WB Positive control:

PC12 cells treated with PMA

WB Recommended dilution:

500-1000