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Background:
This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis. Expression of this gene may be a marker for cancer, and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes.
Applications:
ELISA, WB
Name of antibody:
SERPINH1
Immunogen:
Synthetic peptide of human SERPINH1
Full name:
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
Synonyms:
CBP1; CBP2; OI10; gp46; AsTP3; HSP47; PIG14; PPROM; RA-A47; SERPINH2
SwissProt:
P50454
ELISA Recommended dilution:
5000-10000
WB Predicted band size:
46 kDa
WB Positive control:
NIH/3T3 cell
WB Recommended dilution:
500-2000