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Background: |
The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including tumor protein 53, histone deacetylase 1, and cyclin-dependent kinase inhibitor 1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
RCHY1 |
Immunogen: |
Fusion protein of human RCHY1 |
Full name: |
ring finger and CHY zinc finger domain containing 1 |
Synonyms: |
ZCHY; ARNIP; CHIMP; PIRH2; RNF199; ZNF363; PRO1996 |
SwissProt: |
Q96PM5 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human esophagus cancer |
IHC Recommend dilution: |
50-200 |
WB Predicted band size: |
30 kDa |
WB Positive control: |
293T, A549, Jurkat, 231 cell lysates |
WB Recommended dilution: |
500-2000 |