兔抗MEIOB多克隆抗体

Background:

Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity in vitro (By similarity).

Applications:

ELISA, IHC

Name of antibody:

MEIOB

Immunogen:

Fusion protein of human MEIOB

Full name:

meiosis specific with OB domains

Synonyms:

gs129; C16orf73

SwissProt:

Q8N635

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer and human ovarian cancer

IHC Recommend dilution:

25-100