兔抗SMAD1(Ab-465)多克隆抗体

Background:

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses.

Applications:

WB, IHC

Name of antibody:

SMAD1(Ab-465)

Immunogen:

Synthesized non-phosphopeptide derived from human Smad1 around the phosphorylation site of serine 465 (I-S-S-V-S(p)).

Full name:

SMAD family member 1

Synonyms：

BSP1; JV41; BSP-1; JV4-1; MADH1; MADR1

SwissProt:

Q15797

IHC positive control:

Human breast carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

52 kDa

WB Positive control:

COS7 cells treated with EGF (200ng/ml, 15mins) lysate

WB Recommended dilution:

500-3000