兔抗RITA1多克隆抗体

Background:

Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.

Applications:

ELISA, IHC

Name of antibody:

RITA1

Immunogen:

Fusion protein of human RITA1

Full name:

RBPJ interacting and tubulin associated 1

Synonyms:

RITA; C12orf52

SwissProt:

Q96K30

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer

IHC Recommend dilution:

50-200