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技术规格
Background:
RBM38 is a cell cycle protein found in the cytosol and the nucleus that exists as two alternatively spliced isoforms, 1 (RNPC1a) and 2 (RNPC1b), of 239 and 121 amino acids, respectively. Independent of p53 expression, RBM38 isoform 1 induces cell cycle arrest in G1 phase through maintaining transcript stability at the 3’-UTR of p21, a regulator of cell cycle progression at S phase. RBM38 is also an mRNA splicing factor that regulates the expression of FGFR2. RBM38 contains one RRM (RNA recognition motif) domain.
Applications:
ELISA, IHC
Name of antibody:
RBM38
Immunogen:
Synthetic peptide of human RBM38
Full name:
RNA binding motif protein 38
Synonyms:
RNPC1; SEB4B; SEB4D; HSRNASEB; dJ800J21.2
SwissProt:
Q9H0Z9
ELISA Recommended dilution:
2000-10000
IHC positive control:
Human esophagus cancer and Human liver cancer
IHC Recommend dilution:
50-300