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Fusion protein corresponding to a region derived from 218-381 amino acids of human ACVR1B |
技术规格
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Full name: |
activin A receptor, type IB |
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Synonyms: |
ALK4; SKR2; ACTRIB; ACVRLK4 |
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Swissprot: |
P36896 |
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Gene Accession: |
BC000254 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants. |
