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英文名称: ANAPC10 Antigen (Recombinant Protein)
别 名: DOC1; APC10
储 存: 冷冻(-20℃)
相关类别: 抗原
概述
Full length fusion protein |
Full name: |
anaphase promoting complex subunit 10 |
Synonyms: |
DOC1; APC10 |
Swissprot: |
Q9UM13 |
Gene Accession: |
BC005217 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940) |