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技术规格
Background:
This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.
Applications:
ELISA, IHC
Name of antibody:
FZD8
Immunogen:
Synthetic peptide of human FZD8
Full name:
frizzled family receptor 8
Synonyms:
FZ-8; hFZ8
SwissProt:
Q9H461
ELISA Recommended dilution:
2000-10000
IHC positive control:
Human esophagus cancer and Human liver cancer
IHC Recommend dilution:
50-200