兔抗GATM多克隆抗体

Background:

This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by cognitive disability, language impairment, and behavioral disorders.

Applications:

ELISA, IHC

Name of antibody:

GATM

Immunogen:

Fusion protein of human GATM

Full name:

glycine amidinotransferase

Synonyms:

AT; AGAT; CCDS3

SwissProt:

P50440

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human colorectal cancer

IHC Recommend dilution:

50-300