兔抗GBA多克隆抗体

Background:

This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, WB

Name of antibody:

GBA

Immunogen:

Synthetic peptide of human GBA

Full name:

glucosylceramidase beta

Synonyms:

GCB; GBA1; GLUC

SwissProt:

P04062

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

60 kDa

WB Positive control:

Mouse heart tissue, Mouse liver tissue, Mouse brain tissue lysates

WB Recommended dilution:

500-2000