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英文名称: CNOT2 Antigen (Recombinant Protein)
别 名: CCR4-NOT transcription complex subunit 2; NOT2; CDC36; NOT2H; HSPC131
储 存: 冷冻(-20℃)
相关类别: 抗原
概述
Fusion protein corresponding to a region derived from 341-540 amino acids of human CNOT2 |
Full name: |
CCR4-NOT transcription complex subunit 2 |
Synonyms: |
NOT2; CDC36; NOT2H; HSPC131 |
Swissprot: |
Q9NZN8 |
Gene Accession: |
BC002597 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene. |