手机扫码访问本站
微信咨询
英文名称： COPS8 Antigen (Recombinant Protein)
别 名： COP9 signalosome subunit 8; COP9; CSN8; SGN8
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
|
Fusion protein corresponding to a region derived from 2-209 amino acids of human COPS8 |
|
Full name: |
COP9 signalosome subunit 8 |
|
Synonyms: |
COP9; CSN8; SGN8 |
|
Swissprot: |
Q99627 |
|
Gene Accession: |
BC003090 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed. |
