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Background: |
This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY). |
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Applications: |
ELISA, IHC |
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Name of antibody: |
GCKR |
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Immunogen: |
Synthetic peptide of human GCKR |
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Full name: |
glucokinase (hexokinase 4) regulator |
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Synonyms： |
GKRP; FGQTL5 |
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SwissProt: |
Q14397 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human colon cancer and Human gastric cancer |
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IHC Recommend dilution: |
100-300 |
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WB Predicted band size: |
69 kDa |
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WB Positive control: |
Mouse liver tissue |
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WB Recommended dilution: |
500-2000 |
