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英文名称： CPSF1 Antigen (Recombinant Protein)
别 名： cleavage and polyadenylation specific factor 1; CPSF160; P/cl.18; HSU37012
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
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Fusion protein corresponding to a region derived from 1244-1443 amino acids of human CPSF1 |
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Full name: |
cleavage and polyadenylation specific factor 1 |
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Synonyms: |
CPSF160; P/cl.18; HSU37012 |
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Swissprot: |
Q10570 |
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Gene Accession: |
BC017232 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Cleavage and polyadenylation specificity factor (CPSF) is a multisubunit complex that plays a central role in 3-prime processing of pre-mRNAs. CPSF recognizes the AAUAAA signal in the pre-mRNA and interacts with other proteins to facilitate both RNA cleavage and poly(A) synthesis. CPSF1 is the largest subunit of the CPSF complex (Murthy and Manley, 1995 [PubMed 7590244]). |
