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Background: |
This gene encodes a protein which may function in signal transduction pathways and whose expression is elevated in germinal cell lymphomas. It contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4. Alternative splicing results in multiple transcript variants encoding different isoforms. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
GCSAM |
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Immunogen: |
Synthetic peptide of human GCSAM |
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Full name: |
germinal center-associated, signaling and motility |
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Synonyms: |
HGAL; GCAT2; GCET2 |
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SwissProt: |
Q8N6F7 |
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IHC positive control: |
Human gastric cancer and human liver cancer |
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IHC Recommend dilution: |
50-200 |