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Background: |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This promotes neural repair after stroke. Additionally, this protein may act as a tumor suppressor and reduced expression of this gene is associated with oral cancer. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
GDF10 |
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Immunogen: |
Synthetic peptide of human GDF10 |
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Full name: |
growth differentiation factor 10 |
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Synonyms: |
BIP; BMP3B; BMP-3b |
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SwissProt: |
P55107 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human tonsil and Human breast cancer |
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IHC Recommend dilution: |
25-50 |
