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Background: |
This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
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Applications: |
ELISA, WB |
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Name of antibody: |
GFAP |
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Immunogen: |
Synthetic peptide of human GFAP |
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Full name: |
glial fibrillary acidic protein |
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Synonyms: |
ALXDRD |
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SwissProt: |
P14136 |
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ELISA Recommended dilution: |
5000-10000 |
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WB Predicted band size: |
50 kDa |
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WB Positive control: |
Mouse brain tissue lysate |
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WB Recommended dilution: |
200-1000 |