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英文名称: DCTD Antigen (Recombinant Protein)
别 名: dCMP deaminase
储 存: 冷冻(-20℃)
相关类别: 抗原
概述
Fusion protein corresponding to a region derived from 1-178 amino acids of human DCTD |
Full name: |
dCMP deaminase |
Swissprot: |
P32321 |
Gene Accession: |
BC001286 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This protein uses zinc as a cofactor for its activity. Two transcript variants encoding different isoforms have been found for this gene. |