兔抗GFRA3多克隆抗体

Background:

GDNF family receptor alpha-3 is a protein that in humans is encoded by the GFRA3 gene. The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin. Widely expressed in adult and fetus which exhibit a similar pattern. Essentially not expressed in the central nervous system, but highly expressed in several sensory and sympathetic ganglia of the peripheral nervous system. Moderate expression in many non-neuronal tissues, particularly those of the digestive and urogenital systems, but high expression in stomach and appendix. Several types of glandular tissues show low expression.

Applications:

ELISA, WB, IHC

Name of antibody:

GFRA3

Immunogen:

Synthetic peptide of human GFRA3

Full name:

GDNF family receptor alpha 3

SwissProt:

O60609

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

20-100

WB Predicted band size:

44 kDa

WB Positive control:

Human fetal kidney and brain tissue

WB Recommended dilution:

1000-3000