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英文名称: EEF1E1 Antigen (Recombinant Protein)
别 名: P18; AIMP3
储 存: 冷冻(-20℃)
相关类别: 抗原
概述
Full length fusion protein |
Full name: |
eukaryotic translation elongation factor 1 epsilon 1 |
Synonyms: |
P18; AIMP3 |
Swissprot: |
O43324 |
Gene Accession: |
BC005291 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. |