EML4抗原（重组蛋白）

Full name:

echinoderm microtubule associated protein like 4

Synonyms:

C2orf2; ELP120; EMAP-4; EMAPL4; ROPP120

Swissprot:

Q9HC35

Gene Accession:

BC008685

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants.