兔抗GKN1多克隆抗体

Background:

Gastrokine 1 (GKN1), a stomach-speci c protein also known as 18 kDa antrum mucosa protein (AMP-18) or foveolin, belongs to the gastrokine family of gastric mucus cell-secreted proteins. The human GKN1 gene has been localized in a region of chromosome 2p13 of about 6 kb and contains 6 exons. GKN1 is expressed only in normal human stomach, but is absent from gastric adenocarcinomas, gastro-esophageal adenocarcinoma cell lines, and other normal and tumor gastro-intestinal tissues. GKN1may play an important role in normal gastric function and may be a gastric tumour suppressor.

Applications:

ELISA, WB, IHC

Name of antibody:

GKN1

Immunogen:

Synthetic peptide of human GKN1

Full name:

gastrokine 1

Synonyms:

FOV; CA11; AMP18; BRICD1; foveolin

SwissProt:

Q9NS71

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human colorectal cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

22 kDa

WB Positive control:

Human stomach tissue lysate

WB Recommended dilution:

500-2000