兔抗ZKSCAN3多克隆抗体

Background:

Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas.

Applications:

ELISA, IHC

Name of antibody:

ZKSCAN3

Immunogen:

Fusion protein of human ZKSCAN3

Full name:

zinc finger with KRAB and SCAN domains 3

Synonyms：

ZF47; Zfp47; ZFP306; ZNF306; ZNF309; zfp-47; ZSCAN13; ZSCAN35; dJ874C20.1; dJ874C20.1.

SwissProt:

Q9BRR0

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human gastric cancer

IHC Recommend dilution:

25-100