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英文名称: INTS11 Antigen (Recombinant Protein)
别 名: integrator complex subunit 11; RC68; INT11; RC-68; CPSF3L; CPSF73L
储 存: 冷冻(-20℃)
相关类别: 抗原
概述
Fusion protein corresponding to a region derived from 401-600 amino acids of human INTS11 |
Full name: |
integrator complex subunit 11 |
Synonyms: |
RC68; INT11; RC-68; CPSF3L; CPSF73L |
Swissprot: |
Q5TA45 |
Gene Accession: |
BC013904 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008] |