IRGM抗原（重组蛋白）

Full name:

immunity-related GTPase family, M

Synonyms:

IFI1; IRGM1; LRG47; LRG-47

Swissprot:

A1A4Y4

Gene Accession:

BC128168

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis.