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英文名称: KCTD17 Antigen (Recombinant Protein)
别 名: potassium channel tetramerization domain containing 17
储 存: 冷冻(-20℃)
相关类别: 抗原
概述
Fusion protein corresponding to a region derived from 8-321 amino acids of human KCTD17 |
Full name: |
potassium channel tetramerization domain containing 17 |
Swissprot: |
Q8N5Z5 |
Gene Accession: |
BC031038 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a protein that belongs to a conserved family of potassium channel tetramerization domain (KCTD)-containing proteins. The encoded protein functions in ciliogenesis by acting as a substrate adaptor for the cullin3-based ubiquitin-conjugating enzyme E3 ligase, and targets trichoplein, a keratin-binding protein, for degradation via polyubiquitinylation. A mutation in this gene is associated with autosomal dominant myoclonic dystonia 26. |