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Background: |
Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes. |
Applications: |
IHC |
Name of antibody: |
TRPS1 |
Immunogen: |
Synthesized peptide derived from N-terminal of human TRPS1. |
Full name: |
trichorhinophalangeal syndrome I |
Synonyms: |
GC79; LGCR |
SwissProt: |
Q9UHF7 |
IHC positive control: |
Human lung carcinoma tissue |
IHC Recommend dilution: |
50-100 |