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技术规格
Background:
TTC12 (tetratricopeptide repeat domain 12), also known as TPARM, is a 705 amino acid cytoplasmic protein containing a TPR repeat domain and three armadillo repeat motifs. TTC12 is expressed in testis, prostate, lung, germinal center B cells, neuroblastoma, teratocarcinoma, colon cancer and gastric cancer. The gene encoding TTC12 is located in a region of human chromosome 11 that is commonly deleted in a variety of cancers, therefore, it is considered a candidate tumor suppressor gene. Human chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome.
Applications:
ELISA, WB, IHC
Name of antibody:
TTC12
Immunogen:
Fusion protein of human TTC12
Full name:
tetratricopeptide repeat domain 12
Synonyms:
TPARM
SwissProt:
Q9H892
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human cervical cancer
IHC Recommend dilution:
30-150
WB Predicted band size:
79 kDa
WB Positive control:
Human bladder transitional cell carcinoma grade 2-3 tissue lysate
WB Recommended dilution:
500-2000