PEA15抗原（重组蛋白）

Full name:

phosphoprotein enriched in astrocytes 15

Synonyms:

PED; MAT1; HMAT1; MAT1H; PEA-15; HUMMAT1H

Swissprot:

Q15121

Gene Accession:

BC002426

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a death effector domain-containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.