兔抗UBE2D3多克隆抗体

Background:

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.

Applications:

ELISA, WB, IHC

Name of antibody:

UBE2D3

Immunogen:

Full length fusion protein

Full name:

ubiquitin conjugating enzyme E2D 3

Synonyms:

UBC4/5; UBCH5C; E2(17)KB3

SwissProt:

P61077

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human colorectal cancer and human tonsil

IHC Recommend dilution:

25-100

WB Predicted band size:

17 kDa

WB Positive control:

NIH/3T3 cell lysate

WB Recommended dilution:

200-1000