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英文名称： SGCD Antigen (Recombinant Protein)
别 名： sarcoglycan delta; SGD; DAGD; 35DAG; CMD1L; SGCDP; SG-delta
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
|
Fusion protein corresponding to a region derived from 90-289 amino acids of human SGCD |
|
Full name: |
sarcoglycan delta |
|
Synonyms: |
SGD; DAGD; 35DAG; CMD1L; SGCDP; SG-delta |
|
Swissprot: |
Q92629 |
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Gene Accession: |
BC020740 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. |
