兔抗UNC5B多克隆抗体

Background:

This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene.

Applications:

ELISA, IHC

Name of antibody:

UNC5B

Immunogen:

Synthetic peptide of human UNC5B

Full name:

unc-5 netrin receptor B

Synonyms:

UNC5H2; p53RDL1

SwissProt:

Q8IZJ1

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human ovarian cancer and Human colorectal cancer

IHC Recommend dilution:

25-100