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英文名称： MSLN Antigen (Recombinant Protein)
别 名： MPF; SMRP
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述
|
Fusion protein corresponding to a region derived from 296-606 amino acids of human MSLN |
技术规格
|
Full name: |
mesothelin |
|
Synonyms: |
MPF; SMRP |
|
Swissprot: |
Q13421 |
|
Gene Accession: |
BC009272 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants. |
