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英文名称： MVP Antigen (Recombinant Protein)
别 名： LRP, VAULT1
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述
Fusion protein corresponding to a C terminal 300 amino acids of human MVP
技术规格
|
Full name: |
major vault protein |
|
Synonyms: |
LRP, VAULT1 |
|
Swissprot: |
Q14764 |
|
Gene Accession: |
BC015623 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. |
