兔抗YBX1多克隆抗体

Background:

This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes.

Applications:

ELISA, IHC

Name of antibody:

YBX1

Immunogen:

Synthetic peptide of human YBX1

Full name:

Y-box binding protein 1

Synonyms:

YB1; BP-8; CSDB; DBPB; YB-1; CBF-A; CSDA2; EFI-A; NSEP1; NSEP-1; MDR-NF1

SwissProt:

P67809

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human cervical cancer and human ovarian cancer

IHC Recommend dilution:

30-150