兔抗MTOR(Phospho-Thr2446)多克隆抗体

Background:

The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.

Applications:

WB

Name of antibody:

MTOR(Phospho-Thr2446)

Immunogen:

Peptide sequence around phosphorylation site of threonine2446(T-R-T(p)-D-S) derived from Human mTOR .

Full name:

mechanistic target of rapamycin (serine/threonine kinase)

Synonyms：

FRAP; FRAP1; FRAP2; RAFT1; RAPT1

SwissProt:

P42345

WB Predicted band size:

289 kDa

WB Positive control:

NIH/3T3 cells lysates treated with Insulin

WB Recommended dilution:

500-1000