兔抗NR3C1多克隆抗体

Background:

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance.

Applications:

ELISA, IHC

Name of antibody:

NR3C1

Immunogen:

Synthetic peptide of human NR3C1

Full name:

nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

Synonyms：

GR; GCR; GRL; GCCR

SwissProt:

P04150

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human thyroid cancer and Human lung cancer

IHC Recommend dilution:

15-50