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英文 名称: Anti-TLR3 rabbit polyclonal antibody
别 名: CD283; IIAE2
相关 类别: 一抗
抗 原: TLR3
储 存: 冷冻(-20℃)
宿 主: Rabbit
反应 种属: Human, Mouse
标 记 物: Unconjugate
克隆类型: rabbit polyclonal
技术规格
Background:
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene.
Applications:
ELISA, WB
Name of antibody:
TLR3
Immunogen:
Fusion protein of human TLR3
Full name:
toll-like receptor 3
Synonyms:
CD283; IIAE2
SwissProt:
O15455
ELISA Recommended dilution:
2000-5000
WB Predicted band size:
104 kDa
WB Positive control:
Raji and K562 cells
WB Recommended dilution:
500-2000